Assessment of the percentage of full recombinant adeno-associated virus particles in a gene therapy drug using CryoTEM

In spite of continuous development of gene therapy vectors with thousands of drug candidates in clinical drug trials there are only a small number approved on the market today stressing the need to have characterization methods to assist in the validation of the drug development process. The level o...

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Detalles Bibliográficos
Autores principales: Colomb-Delsuc, Mathieu, Raim, Roman, Fiedler, Christian, Reuberger, Stefan, Lengler, Johannes, Nordström, Rickard, Ryner, Martin, Folea, Ioana Mihaela, Kraus, Barbara, Hernandez Bort, Juan A., Sintorn, Ida-Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165851/
https://www.ncbi.nlm.nih.gov/pubmed/35657790
http://dx.doi.org/10.1371/journal.pone.0269139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165851/
https://www.ncbi.nlm.nih.gov/pubmed/35657790
http://dx.doi.org/10.1371/journal.pone.0269139

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