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Additive genetic effect of GCKR, G6PC2, and SLC30A8 variants on fasting glucose levels and risk of type 2 diabetes

Impaired glucose tolerance is a major risk factor for type 2 diabetes (T2D) and several cardiometabolic disorders. To identify genetic loci underlying fasting glucose levels, we conducted an analysis of 9,232 individuals of European ancestry who at enrollment were either nondiabetic or had untreated...

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Detalles Bibliográficos
Autores principales: Chen, Guanjie, Shriner, Daniel, Zhang, Jianhua, Zhou, Jie, Adikaram, Poorni, Doumatey, Ayo P., Bentley, Amy R., Adeyemo, Adebowale, Rotimi, Charles N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165855/
https://www.ncbi.nlm.nih.gov/pubmed/35657990
http://dx.doi.org/10.1371/journal.pone.0269378