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Additive genetic effect of GCKR, G6PC2, and SLC30A8 variants on fasting glucose levels and risk of type 2 diabetes
Impaired glucose tolerance is a major risk factor for type 2 diabetes (T2D) and several cardiometabolic disorders. To identify genetic loci underlying fasting glucose levels, we conducted an analysis of 9,232 individuals of European ancestry who at enrollment were either nondiabetic or had untreated...
Autores principales: | Chen, Guanjie, Shriner, Daniel, Zhang, Jianhua, Zhou, Jie, Adikaram, Poorni, Doumatey, Ayo P., Bentley, Amy R., Adeyemo, Adebowale, Rotimi, Charles N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165855/ https://www.ncbi.nlm.nih.gov/pubmed/35657990 http://dx.doi.org/10.1371/journal.pone.0269378 |
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