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Detection of infiltrating fibroblasts by single-cell transcriptomics in human kidney allografts

We tested the hypothesis that single-cell RNA-sequencing (scRNA-seq) analysis of human kidney allograft biopsies will reveal distinct cell types and states and yield insights to decipher the complex heterogeneity of alloimmune injury. We selected 3 biopsies of kidney cortex from 3 individuals for sc...

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Detalles Bibliográficos
Autores principales: Suryawanshi, Hemant, Yang, Hua, Lubetzky, Michelle, Morozov, Pavel, Lagman, Mila, Thareja, Gaurav, Alonso, Alicia, Li, Carol, Snopkowski, Catherine, Belkadi, Aziz, Mueller, Franco B., Lee, John R., Dadhania, Darshana M., Salvatore, Steven P., Seshan, Surya V., Sharma, Vijay K., Suhre, Karsten, Suthanthiran, Manikkam, Tuschl, Thomas, Muthukumar, Thangamani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165878/
https://www.ncbi.nlm.nih.gov/pubmed/35657798
http://dx.doi.org/10.1371/journal.pone.0267704