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Efficacy and safety of FOLFIRI/aflibercept (FA) in an elderly population with metastatic colorectal cancer (mCRC) after failure of an oxaliplatin-based regimen

BACKGROUND: The VELOUR study showed the benefit of FOLFIRI-Aflibercept (FA) versus FOLFIRI in patients with metastatic colorectal cancer (mCRC) in second-line treatment. However, only 36% of the included patients were ≥65 years. Thus, we seek to evaluate the efficacy and safety of FA in the elderly...

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Detalles Bibliográficos
Autores principales: Martínez-Lago, Nieves, Cameselle García, Soledad, Alonso de Castro, Beatriz, Gómez-Randulfe Rodríguez, Martín I., Carmona Campos, Marta, González Villarroel, Paula, Salgado Fernández, Mercedes, De la Cámara Gómez, Juan C., Romero Reinoso, Carlos, Cousillas Castiñeiras, Antía, Méndez Méndez, José Carlos, Vidal Insua, Yolanda, Fernández-Montes, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165891/
https://www.ncbi.nlm.nih.gov/pubmed/35657983
http://dx.doi.org/10.1371/journal.pone.0269399