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Muscarinic receptor activation in colon cancer selectively augments pro-proliferative microRNA-21, microRNA-221 and microRNA-222 expression

Overexpression of M3 subtype muscarinic receptors (M(3)R) hastens colon cancer progression. As microRNA (miRNA) expression is commonly dysregulated in cancer, we used microarrays to examine miRNA profiles in muscarinic receptor agonist-treated human colon cancer cells. We used quantitative RT-PCR (q...

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Detalles Bibliográficos
Autores principales: Larabee, Shannon M., Cheng, Kunrong, Raufman, Jean-Pierre, Hu, Shien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165902/
https://www.ncbi.nlm.nih.gov/pubmed/35657974
http://dx.doi.org/10.1371/journal.pone.0269618