α-Catenin links integrin adhesions to F-actin to regulate ECM mechanosensing and rigidity dependence

Both cell–cell and cell–matrix adhesions are regulated by mechanical signals, but the mechanobiological processes that mediate the cross talk between these structures are poorly understood. Here we show that α-catenin, a mechanosensitive protein that is classically linked with cadherin-based adhesio...

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Detalles Bibliográficos
Autores principales: Mukherjee, Abhishek, Melamed, Shay, Damouny-Khoury, Hana, Amer, Malak, Feld, Lea, Nadjar-Boger, Elisabeth, Sheetz, Michael P., Wolfenson, Haguy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166284/
https://www.ncbi.nlm.nih.gov/pubmed/35652786
http://dx.doi.org/10.1083/jcb.202102121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166284/
https://www.ncbi.nlm.nih.gov/pubmed/35652786
http://dx.doi.org/10.1083/jcb.202102121

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