Dietary intervention preserves β cell function in mice through CTCF-mediated transcriptional reprogramming

Pancreatic β cell plasticity is the primary determinant of disease progression and remission of type 2 diabetes (T2D). However, the dynamic nature of β cell adaptation remains elusive. Here, we establish a mouse model exhibiting the compensation-to-decompensation adaptation of β cell function in res...

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Detalles Bibliográficos
Autores principales: Wang, Ruo-Ran, Qiu, Xinyuan, Pan, Ran, Fu, Hongxing, Zhang, Ziyin, Wang, Qintao, Chen, Haide, Wu, Qing-Qian, Pan, Xiaowen, Zhou, Yanping, Shan, Pengfei, Wang, Shusen, Guo, Guoji, Zheng, Min, Zhu, Lingyun, Meng, Zhuo-Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166293/
https://www.ncbi.nlm.nih.gov/pubmed/35652891
http://dx.doi.org/10.1084/jem.20211779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166293/
https://www.ncbi.nlm.nih.gov/pubmed/35652891
http://dx.doi.org/10.1084/jem.20211779

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