Sorafenib targets and inhibits the oncogenic properties of endometrial cancer stem cells via the RAF/ERK pathway

BACKGROUND: Distinct subsets of cancer stem cells (CSCs) drive the initiation and progression of malignant tumors via enhanced self-renewal and development of treatment/apoptosis resistance. Endometrial CSC-selective drugs have not been successfully developed because most endometrial cell lines do n...

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Detalles Bibliográficos
Autores principales: Takao, Tomoka, Masuda, Hirotaka, Kajitani, Takashi, Miki, Fumie, Miyazaki, Kaoru, Yoshimasa, Yushi, Katakura, Satomi, Tomisato, Shoko, Uchida, Sayaka, Uchida, Hiroshi, Tanaka, Mamoru, Maruyama, Tetsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166406/
https://www.ncbi.nlm.nih.gov/pubmed/35659728
http://dx.doi.org/10.1186/s13287-022-02888-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166406/
https://www.ncbi.nlm.nih.gov/pubmed/35659728
http://dx.doi.org/10.1186/s13287-022-02888-y

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