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Metabolic engineering of Pichia pastoris for myo-inositol production by dynamic regulation of central metabolism

BACKGROUND: The methylotrophic budding yeast Pichia pastoris GS115 is a powerful expression system and hundreds of heterologous proteins have been successfully expressed in this strain. Recently, P. pastoris has also been exploited as an attractive cell factory for the production of high-value bioch...

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Detalles Bibliográficos
Autores principales: Zhang, Qiquan, Wang, Xiaolu, Luo, Huiying, Wang, Yaru, Wang, Yuan, Tu, Tao, Qin, Xing, Su, Xiaoyun, Huang, Huoqing, Yao, Bin, Bai, Yingguo, Zhang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166411/
https://www.ncbi.nlm.nih.gov/pubmed/35659241
http://dx.doi.org/10.1186/s12934-022-01837-x