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CD4 T-cell depletion prevents Lassa fever associated hearing loss in the mouse model

Lassa virus (LASV) is the causative agent of Lassa fever (LF), which presents as a lethal hemorrhagic disease in severe cases. LASV-induced hearing loss in survivors is a huge socioeconomic burden, however, the mechanism(s) leading to hearing loss is unknown. In this study, we evaluate in a mouse LF...

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Detalles Bibliográficos
Autores principales: Maruyama, Junki, Reyna, Rachel A., Kishimoto-Urata, Megumi, Urata, Shinji, Manning, John T., Harsell, Nantian, Cook, Rebecca, Huang, Cheng, Nikolich-Zugich, Janko, Makishima, Tomoko, Paessler, Slobodan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166448/
https://www.ncbi.nlm.nih.gov/pubmed/35605008
http://dx.doi.org/10.1371/journal.ppat.1010557