Hypoxia-inducible factors: master regulators of hypoxic tumor immune escape

Hypoxia, a common feature of the tumor microenvironment in various types of cancers, weakens cytotoxic T cell function and causes recruitment of regulatory T cells, thereby reducing tumoral immunogenicity. Studies have demonstrated that hypoxia and hypoxia-inducible factors (HIFs) 1 and 2 alpha (HIF...

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Detalles Bibliográficos
Autores principales: Wu, Qinghua, You, Li, Nepovimova, Eugenie, Heger, Zbynek, Wu, Wenda, Kuca, Kamil, Adam, Vojtech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166526/
https://www.ncbi.nlm.nih.gov/pubmed/35659268
http://dx.doi.org/10.1186/s13045-022-01292-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166526/
https://www.ncbi.nlm.nih.gov/pubmed/35659268
http://dx.doi.org/10.1186/s13045-022-01292-6

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