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Differentially targeted seeding reveals unique pathological alpha-synuclein propagation patterns

Parkinson’s disease is a progressive neurodegenerative disorder characterized by the intracellular accumulation of insoluble alpha-synuclein aggregates into Lewy bodies and neurites. Increasing evidence indicates that Parkinson’s disease progression results from the spread of pathologic alpha-synucl...

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Detalles Bibliográficos
Autores principales: Rahayel, Shady, Mišić, Bratislav, Zheng, Ying-Qiu, Liu, Zhen-Qi, Abdelgawad, Alaa, Abbasi, Nooshin, Caputo, Anna, Zhang, Bin, Lo, Angela, Kehm, Victoria, Kozak, Michael, Yoo, Han Soo, Dagher, Alain, Luk, Kelvin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166565/
https://www.ncbi.nlm.nih.gov/pubmed/34910119
http://dx.doi.org/10.1093/brain/awab440