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High resolution microfluidic assay and probabilistic modeling reveal cooperation between T cells in tumor killing

Cytotoxic T cells are important components of natural anti-tumor immunity and are harnessed in tumor immunotherapies. Immune responses to tumors and immune therapy outcomes largely vary among individuals, but very few studies examine the contribution of intrinsic behavior of the T cells to this hete...

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Detalles Bibliográficos
Autores principales: Ronteix, Gustave, Jain, Shreyansh, Angely, Christelle, Cazaux, Marine, Khazen, Roxana, Bousso, Philippe, Baroud, Charles N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166723/
https://www.ncbi.nlm.nih.gov/pubmed/35661707
http://dx.doi.org/10.1038/s41467-022-30575-2