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Hypoxia promotes a perinatal-like progenitor state in the adult murine epicardium

The epicardium is a reservoir of progenitors that give rise to coronary vasculature and stroma during development and mediates cardiac vascular repair. However, its role as a source of progenitors in the adult mammalian heart remains unclear due to lack of clear lineage markers and single-cell cultu...

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Detalles Bibliográficos
Autores principales: Sayed, Angeliqua, Turoczi, Szimonetta, Soares-da-Silva, Francisca, Marazzi, Giovanna, Hulot, Jean-Sebastien, Sassoon, David, Valente, Mariana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166725/
https://www.ncbi.nlm.nih.gov/pubmed/35661120
http://dx.doi.org/10.1038/s41598-022-13107-2