SGLT2 inhibitor activates the STING/IRF3/IFN-β pathway and induces immune infiltration in osteosarcoma

SGLT2 (sodium-glucose cotransporter 2) is an important mediator of epithelial glucose transport and has been reported that SGLT2, robustly and diffusely expressed in malignant cancer cells, was overexpressed in various tumors, and inhibiting the SGLT2 expression significantly inhibited tumor progres...

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Detalles Bibliográficos
Autores principales: Wu, Wei, Zhang, Zhenhao, Jing, Doudou, Huang, Xin, Ren, Dianyun, Shao, Zengwu, Zhang, Zhicai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166744/
https://www.ncbi.nlm.nih.gov/pubmed/35662245
http://dx.doi.org/10.1038/s41419-022-04980-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166744/
https://www.ncbi.nlm.nih.gov/pubmed/35662245
http://dx.doi.org/10.1038/s41419-022-04980-w

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