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SGLT2 inhibitor activates the STING/IRF3/IFN-β pathway and induces immune infiltration in osteosarcoma
SGLT2 (sodium-glucose cotransporter 2) is an important mediator of epithelial glucose transport and has been reported that SGLT2, robustly and diffusely expressed in malignant cancer cells, was overexpressed in various tumors, and inhibiting the SGLT2 expression significantly inhibited tumor progres...
Autores principales: | Wu, Wei, Zhang, Zhenhao, Jing, Doudou, Huang, Xin, Ren, Dianyun, Shao, Zengwu, Zhang, Zhicai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166744/ https://www.ncbi.nlm.nih.gov/pubmed/35662245 http://dx.doi.org/10.1038/s41419-022-04980-w |
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