Upregulation of the serine palmitoyltransferase subunit SPTLC2 by endoplasmic reticulum stress inhibits the hepatic insulin response

Endoplasmic reticulum (ER) stress is induced by various conditions, such as inflammation and the presence of excess nutrients. Abnormal accumulation of unfolded proteins leads to the activation of a collective signaling cascade, termed the unfolded protein response (UPR). ER stress is reported to pe...

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Detalles Bibliográficos
Autores principales: Kim, Goon-Tae, Devi, Shivani, Sharma, Amitesh, Cho, Kyung-Hee, Kim, Su-Jung, Kim, Bo-Rahm, Kwon, Sang-Ho, Park, Tae-Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166747/
https://www.ncbi.nlm.nih.gov/pubmed/35513574
http://dx.doi.org/10.1038/s12276-022-00766-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166747/
https://www.ncbi.nlm.nih.gov/pubmed/35513574
http://dx.doi.org/10.1038/s12276-022-00766-4

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