CCN1 interacts with integrins to regulate intestinal stem cell proliferation and differentiation

Intestinal stem cells (ISCs) at the crypt base contribute to intestinal homeostasis through a balance between self-renewal and differentiation. However, the molecular mechanisms regulating this homeostatic balance remain elusive. Here we show that the matricellular protein CCN1/CYR61 coordinately re...

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Detalles Bibliográficos
Autores principales: Won, Jong Hoon, Choi, Jacob S., Jun, Joon-Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166801/
https://www.ncbi.nlm.nih.gov/pubmed/35660741
http://dx.doi.org/10.1038/s41467-022-30851-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166801/
https://www.ncbi.nlm.nih.gov/pubmed/35660741
http://dx.doi.org/10.1038/s41467-022-30851-1

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