Aquaporin-4 prevents exaggerated astrocytosis and structural damage in retinal inflammation

ABSTRACT: Aquaporin-4 (AQP4) is the molecular target of the immune response in neuromyelitis optica (NMO) that leads to severe structural damage in the central nervous system (CNS) and in the retina. Conversely, AQP4 might be upregulated in astrocytes as a compensatory event in multiple sclerosis. T...

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Detalles Bibliográficos
Autores principales: Maisam Afzali, Ali, Stüve, Lasse, Pfaller, Monika, Aly, Lilian, Steiger, Katja, Knier, Benjamin, Korn, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166880/
https://www.ncbi.nlm.nih.gov/pubmed/35536323
http://dx.doi.org/10.1007/s00109-022-02202-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166880/
https://www.ncbi.nlm.nih.gov/pubmed/35536323
http://dx.doi.org/10.1007/s00109-022-02202-6

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