Essential role of CK2α for the interaction and stability of replication fork factors during DNA synthesis and activation of the S-phase checkpoint

The ataxia telangiectasia mutated and Rad3-related (ATR)-CHK1 pathway is the major signalling cascade activated in response to DNA replication stress. This pathway is associated with the core of the DNA replication machinery comprising CDC45, the replicative MCM2-7 hexamer, GINS (altogether forming...

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Detalles Bibliográficos
Autores principales: Guerra, Barbara, Doktor, Thomas K., Frederiksen, Sabrina B., Somyajit, Kumar, Andresen, Brage S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166893/
https://www.ncbi.nlm.nih.gov/pubmed/35661926
http://dx.doi.org/10.1007/s00018-022-04374-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166893/
https://www.ncbi.nlm.nih.gov/pubmed/35661926
http://dx.doi.org/10.1007/s00018-022-04374-3

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