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Pretreatment with Panaxatriol Saponin Attenuates Mitochondrial Apoptosis and Oxidative Stress to Facilitate Treatment of Myocardial Ischemia-Reperfusion Injury via the Regulation of Keap1/Nrf2 Activity

Myocardial ischemia-reperfusion injury (MIRI) is a type of severe injury to the ischemic myocardium that can occur following recovery of blood flow, and for which, there is no effective treatment. Panaxatriol saponin (PTS), a major active component of P. notoginseng, has been used clinically to trea...

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Detalles Bibliográficos
Autores principales: Yao, Huan, Xie, Qian, He, Qingman, Zeng, Lei, Long, Jing, Gong, Yuanyuan, Li, Xueping, Liu, Weiwei, Xu, Zhiyi, Wu, Huihui, Zheng, Chuan, Gao, Yongxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166985/
https://www.ncbi.nlm.nih.gov/pubmed/35669855
http://dx.doi.org/10.1155/2022/9626703