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Bushen Huoxue Formula Modulates Autophagic Flux and Inhibits Apoptosis to Protect Nucleus Pulposus Cells by Restoring the AMPK/SIRT1 Pathway

BACKGROUND: Low back pain (LBP) has the characteristics of chronic and persistence, which is a heavy social burden. Intervertebral disc degeneration (IVDD) is a major cause of LBP. The typical features of IVDD are extracellular matrix (ECM) degradation and nucleus pulposus cell (NP) apoptosis. Bushe...

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Detalles Bibliográficos
Autores principales: Gao, Shang, Li, Nianhu, Chen, Renchang, Su, Youxiang, Song, Yun, Liang, Songlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167005/
https://www.ncbi.nlm.nih.gov/pubmed/35669720
http://dx.doi.org/10.1155/2022/8929448