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Phase 1/2 study of topical submicron particle paclitaxel for cutaneous metastases of breast cancer

PURPOSE: This Phase 1/2 study evaluated safety and efficacy of a topical submicron particle paclitaxel (SPP) in an anhydrous ointment base (SOR007), primarily in breast cancer patients with cutaneous metastases (CM). METHODS: One of three concentrations of SOR007 SPP (0.15%, 1.0%, or 2.0%) was appli...

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Detalles Bibliográficos
Autores principales: Lacouture, Mario E., Goldfarb, Shari B., Markova, Alina, Chawla, Sant P., Dewnani, Karan, Iacobucci, Marc, Lang, Julie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167189/
https://www.ncbi.nlm.nih.gov/pubmed/35471470
http://dx.doi.org/10.1007/s10549-022-06584-6