Tip-end fusion of a rod-shaped secretory organelle

Weibel–Palade bodies (WPB) are elongated, rod-like secretory organelles unique to endothelial cells that store the pro-coagulant von-Willebrand factor (VWF) and undergo regulated exocytosis upon stimulation with Ca(2+)- or cAMP-raising agonists. We show here that WPB preferentially initiate fusion w...

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Detalles Bibliográficos
Autores principales: Naß, Johannes, Koerdt, Sophia N., Biesemann, Anja, Chehab, Tarek, Yasuda, Takao, Fukuda, Mitsunori, Martín-Belmonte, Fernando, Gerke, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167223/
https://www.ncbi.nlm.nih.gov/pubmed/35660980
http://dx.doi.org/10.1007/s00018-022-04367-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167223/
https://www.ncbi.nlm.nih.gov/pubmed/35660980
http://dx.doi.org/10.1007/s00018-022-04367-2

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