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Tip-end fusion of a rod-shaped secretory organelle
Weibel–Palade bodies (WPB) are elongated, rod-like secretory organelles unique to endothelial cells that store the pro-coagulant von-Willebrand factor (VWF) and undergo regulated exocytosis upon stimulation with Ca(2+)- or cAMP-raising agonists. We show here that WPB preferentially initiate fusion w...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167223/ https://www.ncbi.nlm.nih.gov/pubmed/35660980 http://dx.doi.org/10.1007/s00018-022-04367-2 |