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SUMO1 Modification of Tau in Progressive Supranuclear Palsy

Small ubiquitin-like modifiers (SUMO) have been implicated in several neurodegenerative diseases. SUMO1 conjugation has been shown to promote aggregation and regulate phosphorylation of the tau protein linked to Alzheimer’s disease and related tauopathies. The current study has demonstrated that SUM...

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Detalles Bibliográficos
Autores principales: Takamura, Hironori, Nakayama, Yoshiaki, Ito, Hidefumi, Katayama, Taiichi, Fraser, Paul E., Matsuzaki, Shinsuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167224/
https://www.ncbi.nlm.nih.gov/pubmed/35567706
http://dx.doi.org/10.1007/s12035-022-02734-5