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SUMO1 Modification of Tau in Progressive Supranuclear Palsy
Small ubiquitin-like modifiers (SUMO) have been implicated in several neurodegenerative diseases. SUMO1 conjugation has been shown to promote aggregation and regulate phosphorylation of the tau protein linked to Alzheimer’s disease and related tauopathies. The current study has demonstrated that SUM...
Autores principales: | Takamura, Hironori, Nakayama, Yoshiaki, Ito, Hidefumi, Katayama, Taiichi, Fraser, Paul E., Matsuzaki, Shinsuke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167224/ https://www.ncbi.nlm.nih.gov/pubmed/35567706 http://dx.doi.org/10.1007/s12035-022-02734-5 |
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