Cdkl5 mutant zebrafish shows skeletal and neuronal alterations mimicking human CDKL5 deficiency disorder

CDKL5 deficiency disorder (CDD) is a rare neurodevelopmental condition characterized primarily by seizures and impairment of cognitive and motor skills. Additional phenotypes include microcephaly, dysmorphic facial features, and scoliosis. Mutations in cyclin-dependent kinase-like 5 (CDKL5) gene, en...

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Detalles Bibliográficos
Autores principales: Varela, Tatiana, Varela, Débora, Martins, Gil, Conceição, Natércia, Cancela, M. Leonor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167277/
https://www.ncbi.nlm.nih.gov/pubmed/35665761
http://dx.doi.org/10.1038/s41598-022-13364-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167277/
https://www.ncbi.nlm.nih.gov/pubmed/35665761
http://dx.doi.org/10.1038/s41598-022-13364-1

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