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Back-translating GWAS findings to animal models reveals a role for Hgfac and Slc39a8 in alcohol and nicotine consumption

Alcohol and tobacco are the most commonly used addictive substances, with high comorbidity rates between alcohol use disorder and tobacco use disorder. Risk for alcohol and nicotine addiction is highly heritable, and they share common genetic factors. A GWAS in over 1 million individuals has reveale...

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Detalles Bibliográficos
Autores principales: Banna, F. K. El, Otto, J. M., Mulloy, S. M., Tsai, W., McElroy, S. M., Wong, A. L., Cutts, G., Vrieze, S. I., Lee, A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167284/
https://www.ncbi.nlm.nih.gov/pubmed/35661789
http://dx.doi.org/10.1038/s41598-022-13283-1