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Macrophage depletion alters bacterial gut microbiota partly through fungal overgrowth in feces that worsens cecal ligation and puncture sepsis mice

Because macrophage dysfunction from some emerging therapies might worsen gut-derived sepsis, cecal ligation and puncture (CLP) sepsis are performed in mice with clodronate-induced macrophage depletion. Macrophage depletion (non-sepsis) increased fecal Ascormycota, with a subtle change in bacterial m...

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Detalles Bibliográficos
Autores principales: Hiengrach, Pratsanee, Panpetch, Wimonrat, Chindamporn, Ariya, Leelahavanichkul, Asada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167291/
https://www.ncbi.nlm.nih.gov/pubmed/35661720
http://dx.doi.org/10.1038/s41598-022-13098-0