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Multiple-reaction monitoring (MRM) LC–MS/MS quantitation of venlafaxine and its O-desmethyl metabolite for a preclinical pharmacokinetic study in rabbits

Preclinical pharmacokinetic (PK) studies in animal models during the formulation development phase give preliminary evidence and near clear picture of the PK behavior of drug and/or its dosage forms before clinical studies on humans and help in the tailoring of the dosage form according to the expec...

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Detalles Bibliográficos
Autores principales: Fazli, Abdul Aala, Panigrahy, Bala Krishna, Kumar, Varinder, Raza, Syed Naiem, Zarger, Bilal Ahmad, Wani, Taha Umair, Ahmad, Shavej, Khuroo, Arshad, Khan, Nisar Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167309/
https://www.ncbi.nlm.nih.gov/pubmed/35661132
http://dx.doi.org/10.1038/s41598-022-13389-6