Preclinical and Toxicology Studies of BRD5529, a Selective Inhibitor of CARD9

BACKGROUND: The caspase recruitment domain-containing protein 9 (CARD9) inhibitor BRD5529 has been shown to be an effective in vitro inhibitor of Pneumocystis β-glucan-induced proinflammatory signaling, suggesting its viability as a candidate for preliminary anti-Pneumocystis drug testing in the rod...

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Detalles Bibliográficos
Autores principales: Kottom, Theodore J., Schaefbauer, Kyle, Carmona, Eva M., Yi, Eunhee S., Limper, Andrew H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167333/
https://www.ncbi.nlm.nih.gov/pubmed/35486318
http://dx.doi.org/10.1007/s40268-022-00389-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167333/
https://www.ncbi.nlm.nih.gov/pubmed/35486318
http://dx.doi.org/10.1007/s40268-022-00389-0

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