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Preclinical and Toxicology Studies of BRD5529, a Selective Inhibitor of CARD9
BACKGROUND: The caspase recruitment domain-containing protein 9 (CARD9) inhibitor BRD5529 has been shown to be an effective in vitro inhibitor of Pneumocystis β-glucan-induced proinflammatory signaling, suggesting its viability as a candidate for preliminary anti-Pneumocystis drug testing in the rod...
Autores principales: | Kottom, Theodore J., Schaefbauer, Kyle, Carmona, Eva M., Yi, Eunhee S., Limper, Andrew H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167333/ https://www.ncbi.nlm.nih.gov/pubmed/35486318 http://dx.doi.org/10.1007/s40268-022-00389-0 |
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