Evaluation of the Effect of Food on the Pharmacokinetics of SHR6390, An Oral CDK4/6 Inhibitor, in Healthy Volunteers

BACKGROUND AND INTRODUCTION: SHR6390 is a new developed highly effective and selective small-molecule oral CDK4/6 inhibitor. We aimed to evaluate the effect of food on the pharmacokinetics of SHR6390 tablets. METHODS: In an open-label two-way crossover study, 24 healthy Chinese volunteers were rando...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Yan-ping, Hu, Ming-hui, Lin, Ping-ping, Li, Ting, Liu, Shu-qin, Wang, Yu-ya, Li, Shao-rong, Li, Xiang-kun, Wang, Chen-jing, Cao, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167418/
https://www.ncbi.nlm.nih.gov/pubmed/35635717
http://dx.doi.org/10.1007/s40268-022-00390-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167418/
https://www.ncbi.nlm.nih.gov/pubmed/35635717
http://dx.doi.org/10.1007/s40268-022-00390-7

Ejemplares similares