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Evaluation of the Effect of Food on the Pharmacokinetics of SHR6390, An Oral CDK4/6 Inhibitor, in Healthy Volunteers

BACKGROUND AND INTRODUCTION: SHR6390 is a new developed highly effective and selective small-molecule oral CDK4/6 inhibitor. We aimed to evaluate the effect of food on the pharmacokinetics of SHR6390 tablets. METHODS: In an open-label two-way crossover study, 24 healthy Chinese volunteers were rando...

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Detalles Bibliográficos
Autores principales:	Liu, Yan-ping, Hu, Ming-hui, Lin, Ping-ping, Li, Ting, Liu, Shu-qin, Wang, Yu-ya, Li, Shao-rong, Li, Xiang-kun, Wang, Chen-jing, Cao, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2022
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167418/ https://www.ncbi.nlm.nih.gov/pubmed/35635717 http://dx.doi.org/10.1007/s40268-022-00390-7

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