Calotropin and corotoxigenin 3-O-glucopyranoside from the desert milkweed Asclepias subulata inhibit the Na(+)/K(+)-ATPase activity

Na(+)/K(+)-ATPase is an essential transmembrane enzyme found in all mammalian cells with critical functions for cell ion homeostasis. The inhibition of this enzyme by several cardiotonic steroids (CTS) has been associated with the cytotoxic effect on cancer cell lines of phytochemicals such as ouaba...

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Detalles Bibliográficos
Autores principales: Meneses-Sagrero, Salvador E., Rascón-Valenzuela, Luisa A., García-Ramos, Juan C., Vilegas, Wagner, Arvizu-Flores, Aldo A., Sotelo-Mundo, Rogerio R., Robles-Zepeda, Ramon E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167584/
https://www.ncbi.nlm.nih.gov/pubmed/35673388
http://dx.doi.org/10.7717/peerj.13524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167584/
https://www.ncbi.nlm.nih.gov/pubmed/35673388
http://dx.doi.org/10.7717/peerj.13524

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