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midline represses Dpp signaling and target gene expression in Drosophila ventral leg development

Ventral leg patterning in Drosophila is controlled by the expression of the redundant T-box Transcription factors midline (mid) and H15. Here, we show that mid represses the Dpp-activated gene Daughters against decapentaplegic (Dad) through a consensus T-box binding element (TBE) site in the minimal...

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Detalles Bibliográficos
Autores principales: Phillips, Lindsay A., Atienza, Markle L., Ryu, Jae-Ryeon, Svendsen, Pia C., Kelemen, Lynn K., Brook, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167623/
https://www.ncbi.nlm.nih.gov/pubmed/35608103
http://dx.doi.org/10.1242/bio.059206