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Dysregulation of adult hippocampal neuroplasticity in major depression: pathogenesis and therapeutic implications

Major depressive disorder (MDD) was previously hypothesized to be a disease of monoamine deficiency in which low levels of monoamines in the synaptic cleft were believed to underlie depressive symptoms. More recently, however, there has been a paradigm shift towards a neuroplasticity hypothesis of d...

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Detalles Bibliográficos
Autores principales: Tartt, Alexandria N., Mariani, Madeline B., Hen, Rene, Mann, J. John, Boldrini, Maura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167750/
https://www.ncbi.nlm.nih.gov/pubmed/35354926
http://dx.doi.org/10.1038/s41380-022-01520-y