Immune Mechanisms of Resistance to Cediranib in Ovarian Cancer

This article investigates mechanisms of resistance to the VEGF receptor inhibitor cediranib in high-grade serous ovarian cancer (HGSOC), and defines rational combination therapies. We used three different syngeneic orthotopic mouse HGSOC models that replicated the human tumor microenvironment (TME)....

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Detalles Bibliográficos
Autores principales: Gopinathan, Ganga, Berlato, Chiara, Lakhani, Anissa, Szabova, Ludmila, Pegrum, Colin, Pedrosa, Ana-Rita, Laforets, Florian, Maniati, Eleni, Balkwill, Frances R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Targeting Drug Resistance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167758/
https://www.ncbi.nlm.nih.gov/pubmed/35313341
http://dx.doi.org/10.1158/1535-7163.MCT-21-0689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167758/
https://www.ncbi.nlm.nih.gov/pubmed/35313341
http://dx.doi.org/10.1158/1535-7163.MCT-21-0689

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