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Immune Mechanisms of Resistance to Cediranib in Ovarian Cancer

This article investigates mechanisms of resistance to the VEGF receptor inhibitor cediranib in high-grade serous ovarian cancer (HGSOC), and defines rational combination therapies. We used three different syngeneic orthotopic mouse HGSOC models that replicated the human tumor microenvironment (TME)....

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Detalles Bibliográficos
Autores principales:	Gopinathan, Ganga, Berlato, Chiara, Lakhani, Anissa, Szabova, Ludmila, Pegrum, Colin, Pedrosa, Ana-Rita, Laforets, Florian, Maniati, Eleni, Balkwill, Frances R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2022
Materias:	Targeting Drug Resistance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167758/ https://www.ncbi.nlm.nih.gov/pubmed/35313341 http://dx.doi.org/10.1158/1535-7163.MCT-21-0689

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