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The Spatial Landscape of Progression and Immunoediting in Primary Melanoma at Single-Cell Resolution

Cutaneous melanoma is a highly immunogenic malignancy that is surgically curable at early stages but life-threatening when metastatic. Here we integrate high-plex imaging, 3D high-resolution microscopy, and spatially resolved microregion transcriptomics to study immune evasion and immunoediting in p...

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Detalles Bibliográficos
Autores principales: Nirmal, Ajit J., Maliga, Zoltan, Vallius, Tuulia, Quattrochi, Brian, Chen, Alyce A., Jacobson, Connor A., Pelletier, Roxanne J., Yapp, Clarence, Arias-Camison, Raquel, Chen, Yu-An, Lian, Christine G., Murphy, George F., Santagata, Sandro, Sorger, Peter K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167783/
https://www.ncbi.nlm.nih.gov/pubmed/35404441
http://dx.doi.org/10.1158/2159-8290.CD-21-1357