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The Spatial Landscape of Progression and Immunoediting in Primary Melanoma at Single-Cell Resolution
Cutaneous melanoma is a highly immunogenic malignancy that is surgically curable at early stages but life-threatening when metastatic. Here we integrate high-plex imaging, 3D high-resolution microscopy, and spatially resolved microregion transcriptomics to study immune evasion and immunoediting in p...
Autores principales: | Nirmal, Ajit J., Maliga, Zoltan, Vallius, Tuulia, Quattrochi, Brian, Chen, Alyce A., Jacobson, Connor A., Pelletier, Roxanne J., Yapp, Clarence, Arias-Camison, Raquel, Chen, Yu-An, Lian, Christine G., Murphy, George F., Santagata, Sandro, Sorger, Peter K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167783/ https://www.ncbi.nlm.nih.gov/pubmed/35404441 http://dx.doi.org/10.1158/2159-8290.CD-21-1357 |
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