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LNP-CpG ODN-adjuvanted varicella-zoster virus glycoprotein E induced comparable levels of immunity with Shingrix™ in VZV-primed mice

Latent varicella-zoster virus (VZV) may be reactivated to cause herpes zoster, which affects one in three people during their lifetime. The currently available subunit vaccine Shingrix™ is superior to the attenuated vaccine Zostavax® in terms of both safety and efficacy, but the supply of its key ad...

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Detalles Bibliográficos
Autores principales: Luan, Ning, Cao, Han, Wang, Yunfei, Lin, Kangyang, Liu, Cunbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167804/
https://www.ncbi.nlm.nih.gov/pubmed/35671982
http://dx.doi.org/10.1016/j.virs.2022.06.002