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Early Developmental PMCA2b Expression Protects From Ketamine-Induced Apoptosis and GABA Impairments in Differentiating Hippocampal Progenitor Cells

PMCA2 is not expressed until the late embryonic state when the control of subtle Ca(2+) fluxes becomes important for neuronal specialization. During this period, immature neurons are especially vulnerable to degenerative insults induced by the N-methyl-D-aspartate (NMDA) receptor blocker, ketamine....

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Detalles Bibliográficos
Autores principales: Lisek, Malwina, Mackiewicz, Joanna, Sobolczyk, Marta, Ferenc, Bozena, Guo, Feng, Zylinska, Ludmila, Boczek, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167922/
https://www.ncbi.nlm.nih.gov/pubmed/35677757
http://dx.doi.org/10.3389/fncel.2022.890827