HLA-I-restricted CD8(+) T cell immunity may accelerate tumorigenesis in conjunction with VHL inactivation

CD8(+) T cells recognize and kill tumor cells with HLA-I tumor antigens in early tumorigenesis, the efficiency of which differs according to antigen-recognition coverage, as shown in earlier tumor onset in HLA-I homozygosity. However, the universality of these associations remains unknown. Here, we...

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Detalles Bibliográficos
Autores principales: Park, BeumJin, Heo, Seok-Jae, Lee, Yong Joon, Seo, Mi-Kyoung, Hong, Jiyun, Shin, Eui-Cheol, Jung, Inkyung, Kim, Sangwoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167969/
https://www.ncbi.nlm.nih.gov/pubmed/35677644
http://dx.doi.org/10.1016/j.isci.2022.104467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167969/
https://www.ncbi.nlm.nih.gov/pubmed/35677644
http://dx.doi.org/10.1016/j.isci.2022.104467

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