Doxorubicin-induced hepatic toxicity in rats: Mechanistic protective role of Omega-3 fatty acids through Nrf2/HO-1 activation and PI3K/Akt/GSK-3β axis modulation

Doxorubicin (DOX), a common antibiotic used to treat a variety of tumors, has several substantial adverse effects that limit its clinical use. As a result, finding effective protective agents to combat DOX-induced organ damage is a necessity. The current study was set to delineate the hepatoprotecti...

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Detalles Bibliográficos
Autores principales: Saleh, Dalia O., Mahmoud, Sawsan S., Hassan, Azza, Sanad, Eman F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167977/
https://www.ncbi.nlm.nih.gov/pubmed/35677895
http://dx.doi.org/10.1016/j.sjbs.2022.103308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167977/
https://www.ncbi.nlm.nih.gov/pubmed/35677895
http://dx.doi.org/10.1016/j.sjbs.2022.103308

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