Synthesis, characterization, DFT analysis and docking studies of a novel Schiff base using 5-bromo salicylaldehyde and β-alanine

Poly(ADP-ribose) polymerase-1(PARP-1) is a DNA-dependent enzyme, forming part of ADP-ribosyltransferase family. Although some PARP inhibitors find therapeutical applications in cancer therapy and exhibits crucial role in DNA damage response. Here a novel Schiff base, (E)-3-((5-bromo-2-hydroxybenzyli...

Descripción completa

Detalles Bibliográficos
Autores principales: Meenukutty, M.S., Mohan, Arsha P., Vidya, V.G., Viju Kumar, V.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167979/
https://www.ncbi.nlm.nih.gov/pubmed/35677407
http://dx.doi.org/10.1016/j.heliyon.2022.e09600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167979/
https://www.ncbi.nlm.nih.gov/pubmed/35677407
http://dx.doi.org/10.1016/j.heliyon.2022.e09600

Ejemplares similares