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Structural dynamics reveal isolate-specific differences at neutralization epitopes on HIV Env
The envelope glycoprotein (Env) is the sole target for neutralizing antibodies against HIV and the most rapidly evolving, variable part of the virus. High-resolution structures of Env trimers captured in the pre-fusion, closed conformation have revealed a high degree of structural similarity across...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167985/ https://www.ncbi.nlm.nih.gov/pubmed/35677643 http://dx.doi.org/10.1016/j.isci.2022.104449 |