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Structural dynamics reveal isolate-specific differences at neutralization epitopes on HIV Env

The envelope glycoprotein (Env) is the sole target for neutralizing antibodies against HIV and the most rapidly evolving, variable part of the virus. High-resolution structures of Env trimers captured in the pre-fusion, closed conformation have revealed a high degree of structural similarity across...

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Detalles Bibliográficos
Autores principales:	Hodge, Edgar A., Naika, Gajendra S., Kephart, Sally M., Nguyen, Adam, Zhu, Richard, Benhaim, Mark A., Guo, Wenjin, Moore, John P., Hu, Shiu-Lok, Sanders, Rogier W., Lee, Kelly K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167985/ https://www.ncbi.nlm.nih.gov/pubmed/35677643 http://dx.doi.org/10.1016/j.isci.2022.104449

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